Title: Live or die: Controlling the fate of cells in a tissue in real time using feedback-control microscopy
Abstract: Think of cells as tiny biological robots in a swarm. Working together in a self-organized fashion, they achieve complex tasks such as wound healing. We aim to study these emergent properties by artificially reprogramming the behaviour of selected cells, and then observing the response of the rest of the cells in the swarm. Using optogenetics, micro-projectors and computer vision, we developed an approach that allows us to control the cell fate (apoptosis, migration, signalling state) of single cells in real time.
The seminar will be online at this link